About Us

People. Science. Answers.

An independent research initiative exploring the biological questions behind opioid exposure.

Independent Research

Exploring the science
with an open mind.

Evidence-Based

Grounded in data
and transparency.

Public Engagement

Working with individuals,
families, and researchers.

A Healthier Tomorrow

Advancing understanding
through science.

Our Mission

Advancing Understanding
Through Science

Smith Genetic Research is an independent research initiative dedicated to exploring the potential long-term biological effects of opioid exposure. We examine emerging evidence from genetic, epigenetic, and clinical research to help inform discussion, guide future research, and support greater public understanding.

Our Research →

Real Questions. Real Science. A Healthier Tomorrow.

Our Founder

Douglas R. Smith, MD

Physician. Researcher. Author.

Dr. Douglas R. Smith is a physician, independent researcher, and author of The Opioid Question. He founded Smith Genetic Research to explore unanswered questions related to opioid exposure, with a focus on genetic and epigenetic research.

His work is driven by a commitment to evidence, transparency, and informed discussion — and a belief that science can help lead to better answers for individuals, families, and future generations.

Learn More About Dr. Smith →

“

“A clear, thoughtful and evidence-based look at one of the most important health questions of our time.”

— Readers

Independent Initiative

Not affiliated with industry
or government.

Evidence-Focused

Built on published research
and regulatory records.

Forward-Looking

Exploring new questions
and future research.

People-Centered

Committed to greater
public understanding.

Our Values

What Guides Our Work

We are guided by a commitment to integrity, scientific rigor, and respect for the individuals and families affected by opioid exposure. Our work is focused on asking important questions, examining the evidence, and contributing to a more informed future.